According to director John Maybury, the love scene between Adrien Brody and Keira Knightley was longer, but was cut because American test audiences did not like the scene, which included nudity.
Mark Wahlberg and Colin Farrell were both considered for the role of Jack Starks before Adrien Brody landed the role.
At one point, "Training Day" director Antoine Fuqua was attached to direct.
'Lady Anne Lambton' was originally cast as Nurse Harding. During principal photography, she fell ill with pancreatitis and was unable to continue filming.
Keira Knightley credits the food poisoning she had during her audition for landing her the part of a sickly alcoholic.
'Keira Knightly' flew in from the set of King Arthur (2004) to audition for her part.
The scenes in the mental hospital were shot in the former Bangour Village Hospital, in West Lothian, Scotland, near Edinburgh. As The Jacket was released, several other film scouts expressed an interest in the hospital building as a location, but the area had already been earmarked for housing development.
Adrien Brody did sessions in an isolation tank, performed prison exercises, and went on a protein diet for his role as war vet Jack Starks.
Scenes of Adrien Brody sobbing in the body drawer were real, for he had asked director John Maybury to keep him locked in even when they weren't filming so he could get the feel of the character's despair. Eventually, Brody lost it during filming, and Maybury caught it on tape.
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